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Antibodies
Anti-Laminin 2 alpha antibody [4H8-2]
Anti-Laminin 2 alpha antibody [4H8-2] from Abcam
(1)
Write a review
Citations:
(53)
Supplier Page
Supplier Page from
Abcam for
Anti-Laminin 2 alpha antibody [4H8-2]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-Laminin 2 alpha antibody [4H8-2]
Company
Abcam
Price
Pricing Info
Supplier Page
View Supplier Product Page
Catalog Number
ab11576
Domain/Region/Terminus
8-2
Antibody Type
Primary
Clone
4H8-2
Clonality
Monoclonal
Isotype
IgG1
Quantity
25 UL
Host
Rat
Applications
Immunohistochemistry (Frozen sections)
Conjugate/Tag
Unconjugated
Concentration
2.2 mg/ml
Research Area
Neuroscience
Gene Name
LAMA2
Reactivity
Mouse
Target
Laminin 2 alpha
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (53)
(1)
Electrical impedance myography detects dystrophin-related muscle changes in mdx mice
Skeletal Muscle
November 18, 2023
Tetsuaki Hiyoshi, Fuqiang Zhao, Rina Baba, Takeshi Hirakawa, Ryosuke Kuboki, Kazunori Suzuki, Yoshiro Tomimatsu, Patricio O’Donnell, Steve Han, Neta Zach,
et al.
thick) were stained for the
cell membrane
with a
rat
monoclonal
anti-laminin 2 alpha antibody (4H8-2
,
ab11576
, dilution
1:1000
;
Abcam
, Cambridge, UK) for 30 min at room temperature. The
cell membrane
of the
muscle
(2)
A cellular and molecular spatial atlas of dystrophic muscle
Proceedings of the National Academy of Sciences of the United States of America
July 18, 2023
Stec MJ, Su Q, Adler C, Zhang L, Golann DR, Khan NP, Panagis L, Villalta SA, Ni M, Wei Y,
et al
.
software (Indica Labs). Primary antibodies were as follows: laminin (
Sigma-Aldrich
,
L9393
&
1:500
;
Abcam
,
ab11576
), F-actin (
1:500
;
Invitrogen
,
A22287
), collagen I (Abcam, ab270993), F4/80 (
Abcam
,
ab6640
), perilipin
(3)
In-Frame Deletion of Dystrophin Exons 8–50 Results in DMD Phenotype
International Journal of Molecular Sciences
May 23, 2023
Tatiana V. Egorova, Ivan I. Galkin, Oleg A. Velyaev, Svetlana G. Vassilieva, Irina M. Savchenko, Vyacheslav A. Loginov, Marina A. Dzhenkova, Diana S. Korshunova, Olga S. Kozlova, Dmitry N. Ivankov,
et al.
(
ab189254
,
1:2000
; Abcam), and co-stained with
rat
monoclonal antibodies raised against laminin 2α [4H8-2] (
ab11576
,
1:250
;
Abcam
) at 4 °C overnight. Antibodies were diluted in a 3% BSA blocking buffer. The following
(4)
Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain Colonization
Cancer research
April 14, 2023
Karreman MA, Bauer AT, Solecki G, Berghoff AS, Mayer CD, Frey K, Hebach N, Feinauer MJ, Schieber NL, Tehranian C,
et al
.
anti-Laminin (
1:100
,
ab30320
,
Abcam
, United Kingdom, RRID:AB_775970),
anti-Laminin 2 alpha
(
1:200
,
ab11576
,
Abcam
, United Kingdom, RRID:AB_298180), anti-MMP9 (
1:100
,
ab38898
,
Abcam
, United Kingdom, RRID:AB_776512),
(5)
Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis
npj Regenerative Medicine
March 15, 2023
Kristen M. Stearns-Reider, Michael R. Hicks, Katherine G. Hammond, Joseph C. Reynolds, Alok Maity, Yerbol Z. Kurmangaliyev, Jesse Chin, Adam Z. Stieg, Nicholas A. Geisse, Sophia Hohlbauch,
et al.
Fitzgerald Industries
), fibronectin (
AB2413
;
1:250
;
Abcam
), laminin (
L9393
;
1:500
;
Sigma-Aldrich
) and laminin alpha-2 (
AB11576
;
1:150
;
Abcam
). Primary antibodies were detected by biotinylated anti-rabbit (
BA-1000
;
1:500
;
Vector Laboratories
(6)
IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological properties
Cellular & molecular biology letters
February 27, 2023
Xiao J, Huang J, Jian X, Wang H, Lan H, Liao Z, Gu R, Hu J, Liao H.
50-0112-82
), rabbit anti-
mouse
dystrophin (
1:500
, Bioss, bs-14477R),
rat
anti-
mouse
laminin (
1:200
,
Abcam
,
ab11576
), rabbit polyclonal anti-fast myosin
muscle
heavy chain (MyHC,
1:500
, abcam,
ab91506
), rabbit anti-
mouse
(7)
The mini-IDLE 3D biomimetic culture assay enables interrogation of mechanisms governing muscle stem cell quiescence and niche repopulation
eLife
December 20, 2022
Erik Jacques, Yinni Kuang, Allison P Kann, Fabien Le Grand, Robert S Krauss, Penney M Gilbert
#
ab203254
"
Anti-M-cadherin
,Mouse IgG1,
1:250
,"
Santa-Cruz
, #
sc-81471
" Anti-Laminin α-2,
Rat
,
1:400
,"
Abcam
, #
ab11576
" Anti-
FoxO3a
,Mouse IgG1,
1:250
,"
Santa-Cruz
, #
sc-48348
" Alexa Fluor 488 Anti-mouse IgG (H+L),Goat,
1:500
,"
Invitrogen
,
(8)
p62/Sqstm1 rescue in muscle retards the progression of steatohepatitis in p62/Sqstm1-null mice fed a high-fat diet
Frontiers in Physiology
November 1, 2022
Ikuru Miura, Kosuke Okada, Akiko Ishii, Eiji Warabi, Takahisa Watahiki, Keii To, Hitoshi Shimano, Shunichi Ariizumi, Junichi Shoda
immunofluorescent staining
,Antibodies for
immunofluorescent staining
Antigen,Supplier,Catalog number,Dilution Laminin 2α,
Abcam
,
ab11576
,
1:500
Slow myosin heavy chain,
Abcam
,
ab234431
,
1:200
Antibodies
for immunoblotting
,Antibodies
for immunoblotting
(9)
Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle loss
Biomaterials
November 1, 2022
Eugenis I, Wu D, Hu C, Chiang G, Huang NF, Rando TA.
ab182981
,
1:500
),
CD68
(
Invitrogen
, FA-11,
1:250
),
CD206
(
Proteintech
,
18704–1-AP
,
1:250
), Laminin (
Abcam
,
ab11576
,
1:500
),
Neurofilament
(
Invitrogen
,
MA5–14981
,
1:250
), Alexa Fluor 594
Donkey
anti-
Rat
(
Invitrogen
,
(10)
Control of backbone chemistry and chirality boost oligonucleotide splice switching activity
Nucleic Acids Research
June 10, 2022
Pachamuthu Kandasamy et al.
(Abcam, Cat. No.
ab15277
,
1:400
diluent) and a monoclonal
rat
anti-laminin antibody (
Abcam
, Cat No.
ab11576
,
1:400
diluent) prepared in antibody dilution buffer (
Invitrogen
, Cat. No.
003218
) overnight at +4°C.
(11)
Bap1/SMN axis in Dpp4+ skeletal muscle mesenchymal cells regulates the neuromuscular system
JCI Insight
May 23, 2022
Ji-Hoon Kim, Jong-Seol Kang, Kyusang Yoo, Jinguk Jeong, Inkuk Park, Jong Ho Park, Joonwoo Rhee, Shin Jeon, Young-Woo Jo, Sang-Hyeon Hann,
et al.
blocking buffer (5%
goat
and
horse
serum in PBS) and incubated overnight with
rat
anti-laminin (
Abcam
,
ab11576
,
1:2000
dilution) in blocking buffer at 4°C. After
incubation
, slides were washed with PBS 3 times and
(12)
CPEB1 directs muscle stem cell activation by reprogramming the translational landscape
Nature communications
February 17, 2022
Zeng W, Yue L, Lam KSW, Zhang W, So WK, Tse EHY, Cheung TH.
were Myod1 (Dako,
Clone
5.8 A,
1:500
), Ki67 (
Abcam
,
ab16667
,
1:100
), Pax7 (DSHB,
1:50
), Laminin (
Abcam
,
ab11576
,
1:1,000
), Syn4 (kind gift from Prof. Dawn Cornelison,
1:500
), CPEB1 (
Abcam
,
Ab73287
,
1:500
), pCPEB1
(13)
Acute T2*-Weighted Magnetic Resonance Imaging Detectable Cerebral Thrombosis in a Rat Model of Subarachnoid Hemorrhage
Translational Stroke Research
February 1, 2022
Jingwei Zhang, Kang Peng, Fenghui Ye, Sravanthi Koduri, Ya Hua, Richard F. Keep, Guohua Xi
were rabbit anti-fibrinogen (
1:200
dilution,
ab34269
,
Abcam
) and
rat
anti-laminin 2α (
1:1200
dilution,
ab11576
,
Abcam
). The secondary Abs were Alexa Fluro 488-conjugated
donkey
anti-
rat
mAb (
1:800
dilution, Invitrogen),
(14)
Low immunogenicity of LNP allows repeated administrations of CRISPR-Cas9 mRNA into skeletal muscle in mice
Nature Communications
December 8, 2021
Eriya Kenjo, Hiroyuki Hozumi, Yukimasa Makita, Kumiko A. Iwabuchi, Naoko Fujimoto, Satoru Matsumoto, Maya Kimura, Yuichiro Amano, Masataka Ifuku, Youichi Naoe,
et al.
anti-dystrophin (cat #
ab15277
, Abcam, Cambridge, UK) or 1000-fold diluted polyclonal
anti-Laminin 2 alpha
(cat #
ab11576
,
Abcam
, Cambridge, UK) for 2 h at room temperature or overnight at 4 °C and then reacted with
goat anti-Rabbit IgG (H;L) antibody
(15)
Simvastatin does not alleviate muscle pathology in a mouse model of Duchenne muscular dystrophy
Skeletal Muscle
December 1, 2021
Olga Mucha, Paulina Podkalicka, Katarzyna Kaziród, Emilia Samborowska, Józef Dulak, Agnieszka Åoboda
Alexa Fluor 488 antibody
,
Thermo Fisher Scientific
) with laminin α2 (rabbit anti-
mouse
antibody,
Abcam
,
ab11576
; secondary antibody:
goat
anti-rabbit Alexa Fluor 568) and showed as a percentage of necrotic fibers
(16)
Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice
Scientific Reports
December 1, 2021
C. Homer-Bouthiette, L. Xiao, Marja M. Hurley
for 10 min at room temperature. Samples were incubated with
anti-laminin 2 alpha
primary antibody (
ab11576
,
Abcam
, Cambridge, UK) or anti-F4/80 primary antibody (
ab6640
,
Abcam
, Cambridge, UK) in blocking solution
(17)
Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axis
Nature Communications
December 1, 2021
Ji-Yun Seo et al.
dilution), or
mouse
anti-MyHC type 2x (DSHB, 6H-1,
1:5
dilution) in addition to
rat
anti-laminin (
Abcam
,
ab11576
,
1:2000
dilution) in 5% BSA blocking buffer. After washes in PBS, sections were incubated for 1 h with
(18)
Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
Cell stem cell
July 1, 2021
Wosczyna MN, Perez Carbajal EE, Wagner MW, Paredes S, Konishi CT, Liu L, Wang TT, Walsh RA, Gan Q, Morrissey CS,
et al
.
,
Santa Cruz
,
Clone
#:E-8 Cat# sc-7273RRID: AB_628115
Laminin
2 alpha monoclonal antibody,
Abcam
,"
Clone
#: 4H8-2Cat#
ab11576
, RRID: AB_298180" Cleaved
Caspase-3
(Asp175) polyclonal antibody,
Cell Signaling
,Cat#
9661S
; RRID:AB_2341188 Sp7/Osterix
(19)
Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties
PloS one
January 1, 2021
Hywood JD, Sadeghipour S, Clayton ZE, Yuan J, Stubbs C, Wong JWT, Cooke JP, Patel S.
frozen in OCT, with 5 μm sections of these samples stained with anti-
CD31
, anti-laminin (
ab25644
and
ab11576
respectively,
Abcam plc
. 330 Science Park, Cambridge CB4, UK) and anti-α
smooth muscle
actin (
F3777
,
(20)
Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
Nature Communications
December 1, 2020
Liam D. Cassidy et al.
Mouse
Blocking Reagent
(MKB-2213) according to manufacturer’s instructions and anti-LAMININ (
Abcam
,
ab11576
,
1:1000
).
Bone marrow transplantation
Atg5i
mice
were backcrossed 11 times to C57BL/6. At 2-month
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Reviews
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(1)
2/23/2017
Laminin Alpha 2 Antibody
Maria Pearce
Laminin 2 alpha antibody is an extracellular protein that plays an important role in the kidney's basement membrane. This antibody helps to identify protein that leads to abnormalities with the ...
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Anti-Laminin 2 alpha antibody [4H8-2] from Abcam
Supplier Page
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Pricing Info
Product Specs
Company Info
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